Beneficial Effect of Thymelaea hirsuta on Pancreatic Islet Degeneration, Renal Fibrosis, and Liver Damages as Demonstrated in Streptozotocin-Induced Diabetic Rat

Table 1

Effect of 200 mg/kg AqTh, 50 mg/kg EaTh, and 10 mg/kg acarbose on daily water and food intake and on body weight gain, in STZ-induced diabetic rats after 4-week treatment.

Groups	Water intake (ml/24 h)		Food intake (g/24 h)		Body weight gain (g)
	Before	After	Before	After
Normal	24.33 ± 4.34	33.00 ± 3.53	18.33 ± 3.00	21.90 ± 1.41	22.88 ± 6.74
Diabetic	70.20 ± 13.64	69.20 ± 14.25	22.14 ± 4.87	29.50 ± 4.96	−6.04 ± 11.10
D + acarbose	56.80 ± 13.08	64.40 ± 15.26	17.30 ± 2.92	28.78 ± 4.20	11.82 ± 4.82
D + AqTh	52.40 ± 6.20	56.60 ± 4.97	21.04 ± 2.89	29.11 ± 1.82	21.88 ± 2.39
D + EaTh	50.40 ± 13.00	80.60 ± 14.42	19.38 ± 4.40	34.00 ± 3.23	14.14 ± 6.05

Each value is mean ± SEM. n = 5-6 rats. AqTh: aqueous extract; EaTh: ethyl acetate fraction. compared with the normal group. compared with the diabetic group. and compared with before treatment in the same group. All statistical tests were used with one-tail value.