Beneficial Effect of Thymelaea hirsuta on Pancreatic Islet Degeneration, Renal Fibrosis, and Liver Damages as Demonstrated in Streptozotocin-Induced Diabetic Rat

Table 2

Effect of 200 mg/kg AqTh, 50 mg/kg EaTh, and 10 mg/kg acarbose on urinary parameters in STZ-induced diabetic rats after 4 weeks treatment.

Groups	Urinary volume (ml/24 h)		Glycosuria (g/l)	Urinary creatinine (mg/dl/24 h)
	Before	After
Normal	10.83 ± 0.84	10.12 ± 0.93	0	41.00 ± 3.42
Diabetic	49.20 ± 12.30	52.20 ± 21.12	36.82 ± 7.75	61.60 ± 8.63
D + acarbose	36.40 ± 12.71	36.84 ± 12.06	29.09 ± 11.90	52.00 ± 8.94
D + AqTh	16.40 ± 4.16	27.72 ± 6.47	17.61 ± 10.24	31.20 ± 9.75
D + EaTh	24.80 ± 7.26	35.40 ± 11.82	19.11 ± 11.81	47.20 ± 10.46

Each value is mean ± SEM. n = 5-6 rats. AqTh: aqueous extract; EaTh: ethyl acetate fraction. compared with before treatment in the same group. and compared with the normal group. compared with the diabetic group. All statistical tests were used with one-tail value.