Beneficial Effect of Thymelaea hirsuta on Pancreatic Islet Degeneration, Renal Fibrosis, and Liver Damages as Demonstrated in Streptozotocin-Induced Diabetic Rat

Table 3

Effect of 200 mg/kg AqTh, 50 mg/kg EaTh, and 10 mg/kg acarbose on liver glycogen, glycosylated hemoglobin, triglyceride, and total cholesterol in STZ-induced diabetic rats after 4-week treatment.

Groups	Liver glycogen (mg/g tissue)	Glycosylated hemoglobin (HbA1c%)	Triglycerides (mg/dl)	Total cholesterol (mg/dl)
Normal	3.97 ± 1.37	4.37 ± 0.24	38.88 ± 7.38	37.48 ± 5.36
Diabetic	0.52 ± 0.12	5.36 ± 0.40	37.48 ± 8.13^ns	45.76 ± 9.13^ns
D + acarbose	1.19 ± 0.77^ns/$	Not measured	57.61 ± 6.10	46.54 ± 11.82
D + AqTh	0.51 ± 0.01	4.61 ± 0.18^ns/$	36.74 ± 4.01	49.97 ± 5.10
D + EaTh	0.65 ± 0.09	5.98 ± 0.79	34.78 ± 6.62	42.79 ± 6.02

Each value is mean ± SEM. n = 4–6 rats. AqTh: aqueous extract; EaTh: ethyl acetate fraction. and compared with the normal group. compared with the diabetic group. All statistical tests were used with one-tail value.