Beneficial Effect of Thymelaea hirsuta on Pancreatic Islet Degeneration, Renal Fibrosis, and Liver Damages as Demonstrated in Streptozotocin-Induced Diabetic Rat

Table 4

Effect of 200 mg/kg AqTh, 50 mg/kg EaTh, and 10 mg/kg acarbose on kidney, liver, and heart weight in STZ-induced diabetic rats after 4-week treatment.

Groups	Kidney (g)	Liver (g)	Heart (g)
Normal	0.34 ± 0.01	3.22 ± 0.09	0.35 ± 0.01
Diabetic	0.44 ± 0.04	3.15 ± 0.13^ns	0.31 ± 0.02^ns
D + acarbose	0.46 ± 0.03	4.18 ± 0.46	0.39 ± 0.02^ns/#
D + AqTh	0.39 ± 0.02	3.18 ± 0.30^ns/$	0.32 ± 0.01^ns/$
D + EaTh	0.39 ± 0.02	3.09 ± 0.14^ns/$	0.33 ± 0.01^ns/$

Each value is mean ± SEM. n = 5-6 rats. AqTh: aqueous extract; EaTh: ethyl acetate fraction. , , and compared with the normal group. and compared with the diabetic group. All statistical tests were used with one-tail value.