Recent Advances of Hepatitis B Detection towards Paper-Based Analytical Devices

Table 4

Electrochemical detection of HBV.

Biomarker	Linearity range	Detection limit	Ref.
Potentiometry
HBsAg	4–960 ng·mL^−1	1.9 ng·mL^−1	[10]
	0.01 ng·mL^−1	0.08–10 ng·mL^−1	[25]
Amperometry
HBsAg	0.0005–10 ng·mL^−1	166 fg·mL^−1	[26]
HBeAg	60 fg·mL^−1−100 ng·mL^−1	20 fg·mL^−1	[27]
HBsAg	10–200 µg·mL^−1	0.17 µg·mL^−1	[28]
Voltammetry
HBsAg	0.001–0.015 ng·mL^−1	0.9 pg·mL^−1	[29]
HBcAg	1.0 to 5.0 ng·mL^−1	0.89 ng·mL^−1	[30]
HBsAg	32 fg·mL^−1−100 ng·mL^−1	10.2 fg·mL^−1	[31]
HBsAg	0.1–300 pg·mL^−1 and 0.1 to 1,000 pg·mL^−1	60 fg·mL^−1 and 10 fg·mL^−1	[32]
HBsAg	20 fg·mL^−1−200 ng·mL^−1	6.7 fg·mL^−1	[33]
HBV DNA	1.10 × 10^3–1.21 × 10^5 copies mL^−1	1100 copies mL^−1	[2]
HBV DNA	0.18 × 10^−6−1.8 × 10^−6 M	2.61 nM	[34]