Palatable Levocetirizine Dihydrochloride Solid Dispersed Fast-Dissolving Films: Formulation and In Vitro and In Vivo Characterization

Table 1

Compositions of fast-dissolving films of levocetirizine dihydrochloride.

Ingredient	LF-1	LF-2	LF-3	LF-4	LF-5	LF-6	LF-7
LCD (mg)	120	120	120	120	—	—	—
LCD: gelatine S.D	—	—	—	—	1 : 0.5	1 : 0.75	1 : 1
HPMC (%)	3	3	3	3	3	3	3
SSG (%)	—	6	—	—	—	—	—
CCS (%)	—	—	6	—	—	—	—
CP (%)	—	—	—	6	6	6	6
PG (ml)	0.2	0.2	0.2	0.2	0.2	0.2	0.2
Sucrose (mg)	34	34	34	34	34	34	34
Vanilla (mg)	14	14	14	14	14	14	14
Citric acid (mg)	13	13	13	13	13	13	13
Water (ml)	20	20	20	20	20	20	20

S.D: solid dispersion.