The Effect of an Extract and Fractions of Date Pits on Some Plasma Constituents, Reproductive Hormones, and Testicular Histology in Male Mice

Table 1

Histological grading system of testicular damage according to the Cosentino classification.

Grade I	Normal testicular architecture with an orderly arrangement of germinal cells.
Grade II	Less orderly, noncohesive germinal cells and closely packed seminiferous tubules.
Grade III	Disordered sloughed germinal cells with shrunken pyknotic nuclei and less distinct seminiferous tubule borders.
Grade IV	Seminiferous tubules are closely packed with coagulative necrosis of the germinal cells.

[22]. Histological changes occur in the contralateral testes of prepubertal rats subjected to various durations of unilateral spermatic cord torsion. J Urol. 133, 906-11.