The Effect of an Extract and Fractions of Date Pits on Some Plasma Constituents, Reproductive Hormones, and Testicular Histology in Male Mice

Table 3

Effects of three different date pit extracts on some plasma parameters in mice.

Parameters/Treatment	Control	Lyophilized extract	Nonpolar fraction extract	Polar fraction extract
Total proteins (g/dL)	5.25 ± 0.36	4.37 ± 0.14	4.18 ± 0.23^a	4.79 ± 0.13
Albumin (g/dL)	1.98 ± 0.12	1.78 ± 0.18	1.46 ± 0.19	1.87 ± 0.08
Alkaline phosphatase (U/L)	18.9 ± 0.95	14.74 ± 1.88	17.09 ± 2.81	20.87 ± 2.43
Aspartate aminotransferase (U/L)	42.93 ± 3.25	53.44 ± 7.37	49.13 ± 6.38	53.40 ± 7.32
Alanine aminotransferase (U/L)	18.49 ± 0.81	16.51 ± 1.94	16.34 ± 2.67	20.44 ± 2.16
Urea (mmol/L)	4.81 ± 0.45	2.75 ± 0.28^a	2.34 ± 0.41^a	2.26 ± 0.41^a
Total cholesterol (mmol/L)	2.32 ± 0.21	2.64 ± 0.30	1.59 ± 0.22	2.10 ± 0.12

The values in the table are the means ± SEM (n = 7). Extracts (100 mg/kg) were given to mice throughout the experiment by oral gavage. On the 28th day of treatment, the mice were sacrificed to collect plasma. Differences between the groups were assessed by one-way analysis of variance (ANOVA) followed by Bonferroni’s multiple comparison test, where . ^adenotes the significance () of the control group vs. different groups. ^bdenotes the significance () of the control group vs. different groups.