Research Article

Describing the Clinical and Laboratory Features and HLA-B Pattern of Adult-Onset Idiopathic Autoimmune Uveitis at a Tertiary Hospital in South India: A Cross-Sectional Study

Table 2

Baseline characteristics.

FeaturesIdiopathic autoimmune uveitis (N = 16)Anterior uveitis (N = 11)Panuveitis (N = 4)Posterior uveitis (N = 1)

Age in years, median (IQR)41 (37–58.2)41 (40–60)41 (23.8–65)37
Female, n (%)10 (62.5)6 (54.5)4 (100)
Uveitis duration in month, median (IQR)24 (6.3–36)12 (6–36)30 (11.3–126)36

Past treatment history
 Treatment refractory, n’ (n)4 (13)2 (8)2 (4)1
 Treatment naïve, n’ (n)5 (13)3 (8)1 (4)
 Treatment responsive, n’ (n)4 (13)3 (8)1 (4)

Tuberculin sensitivity test, n’ (n)
 Interferon gamma release assay, n’ (n)3 (12)2 (7)1 (3)0 (1)
 CXR PA view for TB, n’ (n)0 (7)0 (3)0 (1)0 (1)
 Sacroiliac MRI, n’ (n)0 (12)0 (9)0 (2)0 (1)
 ANA (IFA), n’ (n)0 (6)0 (5)0 (1)
 AntiPR3/MPO, n’ (n)2 (5)1 (3)1 (1)
 ACE, n’ (n)0 (5)0 (3)0 (1)0 (1)
 CRP, median (IQR)0 (12)0 (7)0 (4)0 (1)
 ESR, median (IQR)5.1 (2–8)5.1 (2.4–8)7.4 (2–32)1.1
 Topical treatment16 (10–40)18 (10–40)16 (15–57)6
 Topical steroid, n (%)15 (93.8)11 (100)4 (100)
 Topical cycloplegics/mydriatics, n (%)12 (75)9 (75)3 (75)

Regional therapy
 Intraocular steroid, n (%)1 (6.3)1 (25)
 Systemic steroids n (%)9 (56.3)4 (36.4)3 (75)
 Intravenous steroid, n (%)4 (25)2 (18.2)1 (25)
 Oral steroid, n (%)8 (50)3 (27.3)3 (75)11

Additional immunosuppression
 Steroid sparing, n (%)7 (43.8)5 (45.5)2 (50)1
 Mycophenolate mofetil, n (%)2 (12.5)2 (50)1
 Methotrexate, n (%)4 (25)3 (27.3)1 (25)
 Sulfasalazine, n (%)3 (18.8)3 (27.3)
 Other therapy, n (%)1 (6.3)1 (25)
 2nd DMARD, n (%)3 (18.8)2 (18.2)1 (25)

n’ = frequency of positive results, n = total number of patients with a variable, N = total number of patients in the group.