Research Article

Describing the Clinical and Laboratory Features and HLA-B Pattern of Adult-Onset Idiopathic Autoimmune Uveitis at a Tertiary Hospital in South India: A Cross-Sectional Study

Table 4

Clinical and laboratory features of retinal vasculitis.

FeaturesRetinal vasculitis (N = 4)No retinal vasculitis (N’ = 12)

Age in years, median (IQR)33 (23.8–49)45 (40–60)
Female gender, n (%)3 (75)7 (58.3)
Uveitis duration, median (IQR)36 (27–126)12 (6–34)
Uveitis laterality unilateral, n (%)4 (100)5 (41.7)

Uveitis type
 Posterior uveitis, n (%)1 (25)
 Panuveitis, n (%)3 (75)1 (8.3)

Past treatment history
 Treatment refractory, n’ (n)1 (4)3 (20)
 Treatment naïve, n’ (n)2 (4)3 (10)
 Treatment responsive, n’ (n)1 (4)3 (40)

Symptoms
 Pain, n (%)2 (50)10 (83.3)
 Redness, n (%)1 (25)11 (91.7)
 Epiphora, n (%)-4 (33.3)
 Photophobia, n (%)7 (58.3)
 Blurring of vision, n (%)4 (100)2 (16.7)
 Black spots, n (%)1 (25)

Examination findings
 Synechiae, n (%)5 (41.7)
 Cataract, n (%)1 (25)2 (16.7)
 Cystoid macular oedema, n (%)1 (25)1 (6.3)
 Optic disc oedema, n (%)2 (50)1 (6.3)
 Vitreous hemorrhages, n (%)
 Optic neuritis, n (%)1 (25)

Extraocular features
 Inflammatory low backache1 (25)5 (41.7)
 Heel pain1 (25)1 (6.3)
 Joint pain4 (33.3)
 More than 1 feature2 (16.7)

Inflammatory markers
 CRP, median (IQR)1.6 (1.1–32)5.4 (2.6–7.9)
 ESR, median (IQR)15.5 (8.3–46.8)18 (10–40)

HLA-B patterns
 B07, n04
 B13, n11
 B15, n03
 B18, n01
 B27, n03
 B35, n31
 B40, n04
 B44, n01
 B51, n02
 B52, n00
 B53, n10
 B55, n01
 B58, n10

n’ = frequency of positive results, n = total number of patients with a variable, N = total number of patients in the group 3.