Comparative Physicochemical Screening and Toxicology of Hydroethanol Extracts of the Parts of Pterocarpus santalinoides l’Hér. ex DC. (Fabaceae) in Wistar Rats

Table 5

Biochemical parameters for rats after 28-day treatment with hydroethanolic leaf, bark of trunk, and bark of root of P. santalinoides.

Parameters	Control	Leaves extract		Bark of trunk extract		Bark of root extract
	(Normal saline)	500 mg/kg	1000 mg/kg	500 mg/kg	1000 mg/kg	500 mg/kg	1000 mg/kg
AST (UI/L)	136,60 ± 23,71	144,60 ± 7,32	146,6 ± 10,23	179,40 ± 30,55	170,2 ± 15,04	125,40 ± 13,97	130,60 ± 5,44
ALT (UI/L)	42,80 ± 6,94	27,00 ± 2,7	31,20 ± 1,96	61,20 ± 6,28	43,60 ± 5,46	40,60 ± 8,94	36,40 ± 2,78
ALP (UI/L)	220,80 ± 24,73	158,80 ± 12,08	234,00 ± 22,78	179,40 ± 30,55	170,20 ± 15,04	92,00 ± 7,39	51,40 ± 5,62
Creatinine (mg/L)	8,80 ± 0,37	7,80 ± 0,73	8,00 ± 0,31	9,60 ± 0,50	8,20 ± 0,58	9,80 ± 0,37	9,00 ± 0,44
Total bilirubin (mg/dL)	10,20 ± 0,86	10,60 ± 1,2	10,20 ± 0,48	12,60 ± 1,07	16,20 ± 2,78	9,00 ± 0,63	8,80 ± 0,37
Total protein (g/L)	75,40 ± 3,61	73,00 ± 3,2	74,00 ± 1,26	80,00 ± 2,32	76,40 ± 1,96	80,20 ± 2,39	87,40 ± 1,47
Urea (mg/L)	54,80 ± 2,51	35,20 ± 2,51	31,20 ± 2,41	41,80 ± 2,87	33,80 ± 1,39	48,80 ± 2,35	37,60 ± 2,37

Values are expressed as mean ± standard error of mean (SEM) (n = 5); , , and ; control group versus extract. AST: aspartate transferase, ALT: alanine aminotransferase, and ALP: alkaline phosphatase.