Acute and Subacute Toxicity Assessment of Andrographolide-2-hydroxypropyl-<i>β</i>-cyclodextrin Complex via Oral and Inhalation Route of Administration in Sprague-Dawley Rats

<div>Photomicrographs of the liver and kidney of male and female rats in subacute oral toxicity of AND-2-HyP-<i>β</i>-CYD complex: (a) normal control, (b) low dose (1/10 of LD50 dose, 200 mg/kg), (c) medium dose (1/5 of LD50, 400 mg/kg), (d) high dose (1/3 of LD50, 666 mg/kg), (e) reversal control of high dose (666 mg/kg), and (f) reversal control. Magnification of 40x was used. No observable signs of toxicity are found in any doses and groups.</div>

The Scientific World Journal

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Figure 1

Figure 1: Acute and Subacute Toxicity Assessment of Andrographolide-2-hydroxypropyl-<i>β</i>-cyclodextrin Complex via Oral and Inhalation Route of Administration in Sprague-Dawley Rats 

Figure 1 | Acute and Subacute Toxicity Assessment of Andrographolide-2-hydroxypropyl-β-cyclodextrin Complex via Oral and Inhalation Route of Administration in Sprague-Dawley Rats 