Research Article
Modulating Effects of the Hydroethanolic Leaf Extract of Persicaria lanigera R. Br. Soják (Polygonaceae) against Acute Inflammation
Figure 7
Effect of PLE on histamine-induced paw oedema in rats. Either chlorpheniramine (4 mg·kg−1, p.o) or PLE (100–600 mg·kg−1, p.o) was administered prophylactically (a, b) prior to oedema induction or therapeutically (c, d). Total paw oedema was determined as AUC (b, d), and data were presented as mean ± S.E.M. ; ; compared to the inflamed control response (two-way ANOVA followed by Dunnet’s post hoc test). The arrow denotes the time of drug administration. ns = nonsignificant; CPM = chlorpheniramine.
(a) |
(b) |
(c) |
(d) |