Modulating Effects of the Hydroethanolic Leaf Extract of Persicaria lanigera R. Br. Soják (Polygonaceae) against Acute Inflammation

Table 1

Observations in the acute toxicity study postoral administration of PLE in rats.

Toxicity signs	Control	100	300	1000	3000	5000
Mortality	NØ	NØ	NØ	NØ	NØ	NØ
Latency (h)	—	—	—	—	—	—
Tremor	0	0	0	0	0	0
Excitement	0	0	0	0	0	0
Convulsion	0	0	0	0	0	0
Respiratory abnormality	0	0	0	0	0	0
Aggression	0	0	0	0	0	0
Agitation	0	0	0	0	0	0
Unusual locomotion	0	0	0	0	0	0
Ataxia	0	0	0	0	0	0
Sedation	0	0	0	0	0	0
Salivation	0	0	0	0	0	0
Defecation	0	0	0	0	1	1
Urination	0	0	0	0	1	1
Diarrhea	0	0	0	0	0	0
Reactivity to touch	0	0	0	0	0	0

0 = normal; 1 = mildly impaired; 2 = moderately impaired; 3 = severely impaired; NØ = no death.