Application of Protein-Protein Interaction Network Analysis in Order to Identify Cervical Cancer miRNA and mRNA Biomarkers

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">miRNA</td><td class="align_center">Degree</td><td class="align_center">Target genes</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">miR-193b-3p</td><td class="align_center">7</td><td class="align_center">MCM8, MCM4, CDC6, MCM10, MCM6, POLA1, POLE2</td></tr><tr><td class="align_left">miR-615-3p</td><td class="align_center">7</td><td class="align_center">TIMELESS, CDC6, MCM10, CDKN2A, TONSL, CDC7, MCM2</td></tr><tr><td class="align_left">miR-34a-5p</td><td class="align_center">5</td><td class="align_center">MCM4, MCM10, CDKN2A, MCM2, MCM6C</td></tr><tr><td class="align_left">miR-24-3p</td><td class="align_center">4</td><td class="align_center">MCM4, MCM10, CDKN2A, DBF4</td></tr><tr><td class="align_left">miR-215-5p</td><td class="align_center">4</td><td class="align_center">MCM10, CDKN2A, CDC7, MCM6C</td></tr><tr><td class="align_left">miR-192-5p</td><td class="align_center">4</td><td class="align_center">MCM10, CDKN2A, CDC7, MCM6C</td></tr><tr><td class="align_left">miR-1304-3pc</td><td class="align_center">4</td><td class="align_center">MCM8, TIMELESS, MCM4, DBF4</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Seven hub miRNAs along with target genes in the miRNA-mRNA regulatory network.</div>

The Scientific World Journal

tab1

Table 1

Table 1: Application of Protein-Protein Interaction Network Analysis in Order to Identify Cervical Cancer miRNA and mRNA Biomarkers 