Ruellia tuberosa L. Extract Improves Histopathology and Lowers Malondialdehyde Levels and TNF Alpha Expression in the Kidney of Streptozotocin-Induced Diabetic Rats

Figure 2

Histopathological profiles of the kidney of (a) healthy rats (group 1), (b) diabetic rats (group 2), (c) diabetic rats that treated with 250 mg/kg body weight extracts per day (group 3), (d) diabetic rats that treated with 375 mg/kg body weight extracts per day (group 4), and (e) diabetic rats that treated with 500 mg/kg body weight extracts per day (group 5). Number 1 shows overview of the kidney with 10× magnification, number 2 shows glomerulus area with 40× magnification, and number 3 shows tubules with 40× magnification. Black arrows show glomerulus, yellow arrows show proximal tubules, and blue arrows show Bowman’s space.

(a)

(b)

(c)

(d)

(e)