Canine Mammary Tumors as a Potential Model for Human Breast Cancer in Comparative Oncology

Figure 2

Representative images of Ki67 and Cox2 staining in canine mammary tumors by IHC. Ki67 protein expression was quantified based on the percentage of cells with positive nuclei. Cox2 protein expression was measured according to the proportion and intensity of cytoplasmic staining. Canine mammary adenocarcinomas with weak, moderate, and strong Ki67 staining as well as weak, moderate, and strong Cox2 staining. Scale bars are equal to 100 µm.