Research Article

Intra-Articular AAV9 α-L-Iduronidase Gene Replacement in the Canine Model of Mucopolysaccharidosis Type I

Figure 11

Serum anti-IDUA antibody levels. All animals had no anti-IDUA antibody at baseline. The high-dose +52 w animal demonstrated extremely high anti-IDUA serologies, while the low-dose +52 w animal did have detectable but very low anti-IDUA antibody levels.