Research Article

Comparing Efficacies of Biopsy and Rapid Urease Testing for H. Pylori at a Single Institution

Table 2

Clinical indicators, treatment, and outcomes.

Total H. pylori pos H. pylori neg value

WBC (TH/mm3)0.5957
 <46 (3%)3 (3%)3 (3%)
 4-11.5145 (72.5%)70 (70%)75 (75%)
 >11.516 (8%)7 (7%)9 (9%)
 N/A33 (16.5%)20 (20%)13 (13%)
Neutrophils0.0249
 Low (<50%)15 (7.5%)2 (12%)13 (13%)
 Normal (50-70%)111 (55.5%)58 (58%)53 (53%)
 High (>70%)21 (10.5%)10 (10%)11 (11%)
Histologic analysis<0.001
 H&E only73 (36.5%)20(20%)53(53%)
 Warthin-Starry127 (63.5%)80(80%)47(47%)
Rapid urease0.001
 Positive40 (20%)37 (37%)3 (3%)
 Negative33 (16.5%)2 (2%)31 (31%)
Inflammation0.0817
 Yes197 (98.5%)100 (100%)97 (97%)
 No3 (1.5%)0 (0%)3 (3%)
Intest metaplasia0.0376
 Positive42 (21%)25 (44%)17 (26%)
 Negative80 (40%)32 (56%)48 (74%)
Serology1
 Positive1 (0.5%)1 (1%)0 (0%)
 Negative0 (0%)0 (0%)0 (0%)
UBT0.3768
 Positive2 (1%)2 (2%)0 (0%)
 Negative1 (0.5%)0 (0%)1 (1%)
Treatment<0.001
 Anti-B + PPI86 (43%)84 (84%)2 (2%)
 Anti-B only2 (1%)0 (0%)2(2%)
 Treatment N/A112 (56%)16 (16%)96(96%)
Posttreatment test
 Histology0.0748
 Positive4 (15%)3 (33%)1 (6%)
 Negative22 (85%)6 (67%)16 (94%)
RU0.1288
 Positive1 (10%)1 (33%)0 (0%)
 Negative9 (90%)2 (67%)7 (100%)
Gastric cancer0.0817
 Yes3(1.5%)3 (3%)0 (0%)
 No197 (97.5%)97 (97%)100 (100%)

Inflammation and intestinal metaplasia were noted on biopsy specimens pretherapy.