Research Article
Comparing Efficacies of Biopsy and Rapid Urease Testing for H. Pylori at a Single Institution
Table 2
Clinical indicators, treatment, and outcomes.
| | Total | H. pylori pos | H. pylori neg | value |
| WBC (TH/mm3) | | | | 0.5957 | <4 | 6 (3%) | 3 (3%) | 3 (3%) | | 4-11.5 | 145 (72.5%) | 70 (70%) | 75 (75%) | | >11.5 | 16 (8%) | 7 (7%) | 9 (9%) | | N/A | 33 (16.5%) | 20 (20%) | 13 (13%) | | Neutrophils | | | | 0.0249 | Low (<50%) | 15 (7.5%) | 2 (12%) | 13 (13%) | | Normal (50-70%) | 111 (55.5%) | 58 (58%) | 53 (53%) | | High (>70%) | 21 (10.5%) | 10 (10%) | 11 (11%) | | Histologic analysis | | | | <0.001 | H&E only | 73 (36.5%) | 20(20%) | 53(53%) | | Warthin-Starry | 127 (63.5%) | 80(80%) | 47(47%) | | Rapid urease | | | | 0.001 | Positive | 40 (20%) | 37 (37%) | 3 (3%) | | Negative | 33 (16.5%) | 2 (2%) | 31 (31%) | | Inflammation | | | | 0.0817 | Yes | 197 (98.5%) | 100 (100%) | 97 (97%) | | No | 3 (1.5%) | 0 (0%) | 3 (3%) | | Intest metaplasia | | | | 0.0376 | Positive | 42 (21%) | 25 (44%) | 17 (26%) | | Negative | 80 (40%) | 32 (56%) | 48 (74%) | | Serology | | | | 1 | Positive | 1 (0.5%) | 1 (1%) | 0 (0%) | | Negative | 0 (0%) | 0 (0%) | 0 (0%) | | UBT | | | | 0.3768 | Positive | 2 (1%) | 2 (2%) | 0 (0%) | | Negative | 1 (0.5%) | 0 (0%) | 1 (1%) | | Treatment | | | | <0.001 | Anti-B + PPI | 86 (43%) | 84 (84%) | 2 (2%) | | Anti-B only | 2 (1%) | 0 (0%) | 2(2%) | | Treatment N/A | 112 (56%) | 16 (16%) | 96(96%) | | Posttreatment test | | | | | Histology | | | | 0.0748 | Positive | 4 (15%) | 3 (33%) | 1 (6%) | | Negative | 22 (85%) | 6 (67%) | 16 (94%) | | RU | | | | 0.1288 | Positive | 1 (10%) | 1 (33%) | 0 (0%) | | Negative | 9 (90%) | 2 (67%) | 7 (100%) | | Gastric cancer | | | | 0.0817 | Yes | 3(1.5%) | 3 (3%) | 0 (0%) | | No | 197 (97.5%) | 97 (97%) | 100 (100%) | |
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Inflammation and intestinal metaplasia were noted on biopsy specimens pretherapy. |