Research Article

Challenges and Outcomes of the First Stem Cell Transplant Program in Tanzania, East Africa

Table 3

Result of the initial gap analysis.

AvailableNot available

Stem cell transplant unit at MNH, mloganzila campus
(i) 6 hepa-filtered rooms(i) Infusion and syringe pumps
(ii) Biomedical equipments including, cardiac monitors, medication carts, crash cart, computers for accessing the hospital and laboratory information systems

Apheresis facility at MNH, upanga campus
(i) Apheresis equipment: Spectra Optia™ cell separator (TERUMOBCT™, Colorado, USA) × 2(i) Optia™ stem cell harvest kit
(ii) ACD bags compatible with Optia™

Stem cell laboratory at MNH, muhimbili campus
(i) BD FACS canto II
(ii) Controlled rate freezer with liquid nitrogen storage tank
(i) Reagents for standardization of CD34+ cell enumeration
(ii) CD34+ cell enumeration beads and reagents
(iii) Software for CD34+ cell enumeration
(iv) Liquid nitrogen shipper
(v) Liquid nitrogen supply

Team
(i) 5 attending physicians and 3 registered nurses (RN), 1 pharmacist, 3 lab scientists and 1 microbiologist had previously undergone training in the clinical management of HSCT patients(i) Trained associate physicians
(ii) Larger team of trained RN
(iii) Trained housekeeping staff

Policies and protocols
(i) Antibiotics and antifungals(i) SOPs for pretransplant workup and consent
(ii) Nursing policies and SOPs
(iii) Infection control policy
(iv) Febrile neutropenia management policy
(v) Central venous access insertion and maintenance bundle
(vi) Transfusion policy
(vii) SOPs for peripheral blood stem cell harvest, storage, transport and infusion
(viii) Non-availability of critical drugs such as melphalan, plerixafor, etc