Research Article
The Association of Anticoagulation Intensity with Outcomes in Hospitalized COVID-19 Patients
| Outcome | Total (n = 915) | Standard-dose prophylaxis (n = 813) | High-dose prophylaxis (n = 32) | Therapeutic anticoagulation (n = 70) | value |
| In-hospital mortality, n (%) | 49 (5.4) | 39 (4.8) | 4 (12.5) | 6 (8.6) | 0.0594 | Intensive care unit transfer, n (%) | 127 (13.9) | 105 (12.9) | 7 (21.9) | 15 (21.4) | 0.0555 | Mechanical ventilation, n (%) | 84 (9.2) | 68 (8.4) | 6 (18.8) | 10 (14.3) | 0.6431 | Vasopressors, n (%) | 75 (8.2) | 59 (7.3) | 6 (18.8) | 10 (14.3) | 0.3111 | Need for packed red blood cell transfusion, n (%) | 43 (4.7) | 35 (4.3) | 4 (12.5) | 4 (5.7) | 0.0833 | Gastrointestinal hemorrhage, n (%) | 11 (1.2) | 8 (1.) | 1 (3.1) | 2 (2.9) | 0.1372 | Intracranial hemorrhage, n (%) | 1 (0.1) | 0 (0) | 1 (3.1) | 0 (0) | 0.0350 |
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Data are n (%) where n is the total number of patients. values comparing all three anticoagulation groups are from Fisher’s exact test. |