The Effect of Clopidogrel and Ticagrelor on Human Adipose Mesenchymal Stem Cell Osteogenic Differentiation Potential: In Vitro Comparative Study

Figure 5

ALP activity after 21 days of osteogenic induction. (a) Representative kinetic profile of ALP assay demonstrating accumulation of the yellow p-nitrophenolate product over time among the different groups. (b) Rate of accumulation of the yellow p-NP was determined by calculating the slope of each reaction. The values reported are the means ± SD of three independent experiments. significant difference of the respective group compared to the control (cells in normal medium). ^# significant difference of the respective group compared to the osteo group (osteogenic medium). ^$ significant difference of the respective group compared to the CLP group. values <0.0001 are statistically significant. Data are expressed as mean ± SD of three independent experiments.

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