New Tin (IV) and Organotin (IV) Complexes with a Hybrid Thiosemicarbazone/Hydrazone Ligand: Synthesis, Crystal Structure, and Antiproliferative Activity

Figure 5

In vitro cytotoxicity measured by MTT. (a) IC₅₀ in different cell lines. (b) Cytotoxic effect of complex 3 (0-5 µM) in cell lines MDA-MB-231, HeLa, PC3, and HepG2 (cancer cells) and WI-38 (normal lung fibroblast cell line). The data have been repeated thrice and the results were expressed as the mean ± SEM. The level of significance was set at ; ; and in respect with the control.

(a)

(b)