Research Article

Association between Interleukin-6 Gene Polymorphism (rs1800795 and rs1800796) and Type 2 Diabetes Mellitus in a Ghanaian Population: A Case-Control Study in the Ho Municipality

Table 3

Comparison of glycaemic and lipid parameters between controls, DM alone, and DM with the HTN groups.

VariablesControlsDM aloneDM with HTN value (a) value (b) value (c)

Lipid profile
TC (mmol/l)0.0320.1021.00
TG (mmol/l)<0.0010.0060.007
HDL-C (mmol/l)0.095<0.0010.511
LDL-C (mmol/l)1.001.001.00
VLDL-C (mmol/l)<0.0010.0170.017
Glycaemic indices
FBG (mmol/l)<0.001<0.0010.001
Insulin (mU/l)<0.001<0.0010.908
HOMA-IR<0.001<0.0010.171

Data are presented as . value (a): post hoc analysis between controls and patients with DM alone. value (b): post hoc analysis between controls and DM with HTN. value (c): post hoc analysis between DM alone and DM with the HTN groups. is significant. Significant values are marked in bold. Analysis was conducted using one-way analysis of variance with the Tukey-Kramer post hoc multiple comparison test. TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; VLDL-C: very low-density lipoprotein cholesterol; FBG: fasting blood glucose; HOMA-IR: homeostatic model assessment for insulin resistance; DM: diabetes mellitus; HTN: hypertension.