Ferroptosis Is a Potential Therapeutic Target for Pulmonary Infectious Diseases

Table 1

Changes in lipid peroxidation and ferroptosis-related features in the case of different factors associated with pulmonary infection.

Infectious factor	ROS	GPX4	Fe^2+	LPO
PA	Increase	/	/	/
MTB	Increase	Decrease	Increase	Increase
SARS-CoV-2	Increase	Decrease	/	/
Staphylococcus aureus	Increase	/	/	Increase
Klebsiella pneumoniae	Increase	/	/	/
Leishmania spp	/	Deficiency	/	Increase

PA: Pseudomonas aeruginosa; MTB: Mycobacterium tuberculosis; SARS-CoV-2: severe acute respiratory syndrome coronavirus Type 2; LPO: lipid peroxides; GPX4: glutathione peroxidase 4; ROS: reactive oxygen species.