Surgical Periodontal Management of Peripheral Ossifying Fibroma: A Series of Three Cases

Table 1

Histological analysis. Common main histological features of all three cases of POF are listed.

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Histological analysis

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(i) Mucosal mass surfaced by parakeratinized stratified squamous epithelium
(ii) Tissue proliferation constituted a nodular configuration, devoid of surface epithelium, also covered by a thick fibrinous layer
(iii) Mesenchymal spindle cell proliferation
(iv) Intertwining bundles of collagen supporting numerous haphazardly arranges of mesenchymal, fibroblast-like cells interspersed by occasional small blood vessels engorged with erythrocytes
(v) Focal areas of osteoid and new bone formation
(vi) Ulcerated benign cellular mesenchymal tissue proliferation supporting bone and cementum-like calcified deposits
(vii) Numerous bone trabeculae containing osteocytes with lacunar and basophilic cementum-like calcified deposits
(viii) Chronic inflammation of the underlying lamina propria
(ix) Neutrophils and extravasated erythrocytes and occasional basophilic bacterial colonies
(x) Inflammatory cells mostly included neutrophils and lymphocytes
(xi) No evidence of malignancy

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