Metastatic Esophageal Adenocarcinoma Presenting as Neck Dermal Metastasis

Figure 2

(a) Results from esophagoscopy show a circumferential fungating and ulcerated mass with friable surfaces was found at the gastroesophageal junction. Esophageal biopsy showing poorly differentiated adenocarcinoma, diffuse type. (b) Unremarkable squamous epithelium is shown on the right and the discohesive tumor cells are on the left. (c) Proliferation of signet ring cells (arrow) with intracellular mucin that displaces the nucleus to the side. (d, e) Immunohistochemical staining shows positive staining in highlighting tumor cells in CK (AE1-AE3) and MUC5AC and negative staining of P63, supporting the diagnosis of adenocarcinoma (f).

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