Case Report

A Case in Which HLA-DR4 is Involved in the Development of Complex Immune-Related Endocrinological Adverse Events following Combination Therapy with Nivolumab and Ipilimumab

Figure 1

Time course for clinical parameters, diagnosis, and treatment. Nivolumab and ipilimumab were administered at 0, 4, 7, 10, 12, 16, and 18 weeks. CPR: C-peptide reactivity; ACTH: adrenocorticotropic hormone; FT4: free thyroxine; TSH: thyroid-stimulating hormone.