Subclinical Cushing’s Disease with High-Molecular-Weight Forms of Adrenocorticotropic Hormone Production

Table 1

The laboratory data for the early morning after admission.

Biochemistry
TP	6.3 g/dL
Alb	3.6 g/dL
T-bil	0.5 mg/dL
AST	16 U/L
ALT	12 U/L
ALP	207 U/L
γ-GTP	55 U/L
BUN	12.4 mg/dL
Cr	0.63 mg/dL
TG	80 mg/dL
LDL-C	217 mg/dL
HDL-C	43 mg/dL
Na	144 mEq/L
K	3.4 mEq/L
Cl	110 mEq/L
HbA1c	5.8%
BG	87 mg/dL
Hematology
WBC	4170 µL
Neutro	2130 µL
Lympho	1680 µL
Mono	220 µL
Eosino	100 µL
Baso	0 µL
Hb	12.2 g/dL
RBC	392 × 10^4 µL
Hct	37.9%
Plt	16.5 × 10^4 µL
Endocrine
ACTH	92.6 pg/mL
Cortisol	7.7 µg/dL
DHEA-S	78 µg/dL
PRL	12.4 ng/mL
TSH	0.893 µIU/mL
Free T3	2.79 pg/mL
Free T4	1.16 ng/dL
FSH	20.2 mIU/mL
LH	10.4 mIU/mL
GH	0.53 ng/mL
IGF-1	77 ng/mL
PAC (CLEIA)	54 pg/mL
PRA	0.6 ng/mL/h
Urinary
pH	6.0
Protein	±
Glucose	—
Occult blood	—

TP, total protein; BG, blood glucose; WBC, white blood cell; Neutro, neutrophil; Lympho, lymphocyte; Mono, monocyte; Eosino, eosinophil; Baso, basophil; Hb, hemoglobin; RBC, red blood cell; Hct, hematocrit; Plt, platelets; ACTH, adrenocorticotropic hormone; DHEA-S, dehydroepiandrosterone sulfate; PRL, prolactin; TSH, thyroid-stimulating hormone; FSH, follicle-stimulating hormone; LH, luteinizing hormone; GH, growth hormone; IGF-1, insulin-like growth factor-1; PAC, plasma aldosterone concentration; CLEIA, chemiluminescent enzyme immunoassay; PRA, plasma renin activity.