Two Extremely Preterm Infants Discharged with a Home High-Flow Nasal Cannula for Severe Bronchopulmonary Dysplasia

Table 1

The table of detailed course for two cases.

	Clinical course	The setting of home HFNC
Case 1; Sex: male; Gestational age: 22 weeks + 6 days; Birth weight: 435 g	Birthday— 45th DOL: invasive ventilation with ETT; 45–152nd DOL: nasal CPAP(biphasic mode); (152–170th DOL: invasive ventilation with ETT, 170–193rd DOL: nasal CPAP (biphasic mode), 193–324th DOL: NIV-NAVA because of acute colonic perforation); 324–404th DOL: HFNC; 404th DOL: discharge with home HFNC to home; At clinic: the parents want to adjust the timing when HFNC was attached or broken off, then we depended on their decision and advised them to elongate the duration of break off	6 L/min (4 L/min of room air and 2 L/min of oxygen); FiO2 ≒ 47.3%
Case 2; Sex: Female; Gestational age: 23 weeks + 5 days; Birth weight: 450 g	Birthday—50th DOL: invasive ventilation with ETT; 50–90th DOL: NIV-NAVA; 90–391th DOL: HFNC (182–191th DOL: invasive ventilation with ETT, 191–193rd DOL: NIV-NAVA, 193rd—HFNC because of acute exacerbation of PH); 391th DOL: discharge with home HFNC to the rehabilitation hospital; At clinic: we first set the timing of break off while the patient is awake, and finally break HFNC off also while she was asleep	6 L/min (5 L/min of room air and 1 L/min of oxygen); FiO2 ≒ 34.1%

ETT: endotracheal tube; DOL: day of life; NIV-NAVA: noninvasive neurally adjusted ventilatory assist.