Colitis as the Initial Presentation of Eosinophilic Granulomatosis with Polyangiitis

Figure 1

Eosinophilic granulomatosis with polyangiitis. (A) Area of patchy erythema and decreased mucosal vascularity in the rectum seen on colonoscopy. (B) Colon mucosal biopsies: low power magnification showed eosinophilic necrotizing granulomatous vasculitis involving the submucosal vessel (×40). (C, D) High-power magnification showed a dense eosinophilic infiltrate destroying the vessel wall, a classic presentation of granulomatous vasculitis (×400).