Case Report
A Rare Case of Acute Methotrexate Toxicity Leading to Bone Marrow Suppression
| | Days | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | Day 7 | Day 21 |
| | WBC | 3.70 | 3.36 | 1.65 | 1.48 | 1.24 | 1.50 | 2.68 | 7.21 | | RBC | 3.74 | 3.48 | 3.35 | 3.26 | 3.19 | 3.03 | 3.10 | 3.41 | | Hemoglobin | 11.4 | 10.8 | 10.4 | 9.9 | 9.1 | 9.1 | 9.5 | 10.3 | | Platelets | 22 | 19 | 15 | 16 | 24 | 34 | 170 | 254 | | Neutrophil % | 69.2 | 58.4 | Not performed | Not performed | 17.7 | Not performed | 27.7 | 62.5 | | Neutrophil # | 2.41 | 1.96 | Not performed | Not performed | 0.22 | Not performed | 0.74 | 4.51 | | Creatinine | 1.77 | 1.28 | 1.08 | 0.99 | 1.06 | 1.00 | 1.13 | 1.04 | | Albumin | 3.3 | 3.1 | Not performed | Not performed | 2.7 | Not performed | Not performed | 3.4 |
|
|
Normal ranges: WBC: 4.5–11.0 × 109/L, RBC: 4.7–6.1 cells/mcL, hemoglobin: 13.8–17.2 g/L, platelets: 150,000–450,000/micro/L, neutrophil %: 40–60%, absolute neutrophil count: 2500–6000, creatinine: 0.7–1.3 mg/dL, albumin: 3.4–5.4 g/dL.
|
