JAK2 as Predictor of Therapeutic Response in Patients with Chronic Myeloid Leukemia Treated with Imatinib

Table 3

Correlation coefficients for JAK2 levels and the presence of a complete hematological response, as well as early molecular response.

Variable	Complete hematological response		Early molecular response
	r	p-Value	r	p-Value
JAK2 levels before imatinib treatment
JAK2 gene	−0.333	0.018	−0.271	0.045
Phosphorylated JAK2	−0.448	0.002	−0.543	<0.001
Total JAK2	−0.477	0.001	−0.520	<0.001
JAK2 levels after 3 months of imatinib treatment
JAK2 gene	−0.605	<0.001	−0.654	<0.001
Phosphorylated JAK2	−0.476	0.001	−0.421	0.003
Total JAK2	−0.141	0.192	−0.157	0.166