Clinical Outcomes and Patient Experience of Biosimilar to Biosimilar Infliximab Switching in Patients with Inflammatory Bowel Disease: A Prospective, Single-Centre, Phase IV Interventional Study with a Nested Qualitative Study

Figure 6

Comparison of cytokine response levels between those who terminated due to patient choice (green circles) versus secondary loss of response (orange circles). Cytokines were arranged according to T helper cytokine profiles (a–f). Both datasets were tested according to the Mann–Whitney test to identify differences between averages. , , , and denote , , , and and n.s denotes not significant.

(a) Th1 cytokines

(b) Th2 cytokines

(c) Th9 cytokines

(d) Th17 cytokines

(e) Th22 cytokines

(f) Treg cytokines