Research Article

Treatment Patterns and Survival in Patients with Intermediate, Advanced, or Terminal Stage of Hepatocellular Carcinoma in France over the Period 2015-2017: A Real-Life Study

Table 1

Characteristics of patients with newly identified IAT stage HCC over the period 2015–2017 in the SNDS database.

Newly diagnosed IAT stage HCC populationTotal
19,649 (100%)

Gender male (%)16,210 (82.5%)
Age (years) at the identification of IAT stage HCC: mean (SD)70.5 (11.0)
Duration of follow-up (month): mean (SD)7.9 (7.3)
History of HCC curative treatment or type of disease progression
 Previous curative treatment3,205 (16.3%)
 No curative treatment (de novo IAT stage at HCC diagnosis)13,512 (68.8%)
 Undetermined (lack of retrospective data in some patients with HCC diagnosed before 2013)2,932 (14.9%)
HCC aetiology (several responses possible)
 Alcohol intake10,328 (52.6%)
 Viral hepatitis3,635 (18.5%)
 Metabolic risk factors§8,729 (44.4%)
 Other liver diseases11,218 (57.1%)
 None identified liver disease in the database2,596 (13.2%)

IAT stage: intermediate, advanced, or terminal stage; a single patient can have several HCC risk factors explaining the sum of percentages greater than 100; §Metabolic risk factors are NAFLD (nonalcoholic fatty liver disease), NASH (nonalcoholic steatohepatitis), or diabetes mellitus.