Research Article

Synthesis, Spectral Characterization, and Biological Activities of Some Metal Complexes Bearing an Unsymmetrical Salen-Type Ligand, (Z)-1-(((2-((E)-(2-Hydroxy-6-methoxybenzylidene)amino)phenyl)amino) methylene) Naphthalen-2(1H)-one

Table 2

Cytotoxicity of H2L and its metal complexes.

CompoundIC50 (µM)
KBHep-G2

H2L46.14 ± 3.7843.29 ± 3.57
[Zn(L).H2O]>250>250
[Cu(L)]>250>250
[Co(L)]4.45 ± 0.267.40 ± 0.62
[Mn(L)]4.68 ± 0.653.67 ± 0.27
[Fe(L)Cl]2.64 ± 0.116.07 ± 0.44
Ellipticine1.22 ± 0.201.34 ± 0.20