Novel Thioethers of Dihydroartemisinin Exhibiting Their Biological Activities

Table 2

α-Glucosidase inhibitory activity of the synthesized products.

Sample’s name	Test concentration (µg/mL)	Inhibition (%)	IC50 (mM)
Voglibose	100	60.33 ± 2.78	0.35 ± 0.06
5a	200	50.05 ± 1.65	0.47 ± 0.01
5b	200	0	—
5c	200	0	—
5d	200	45.50 ± 1.29	—
5e	200	94.92 ± 1.82	0.21 ± 0.02
5f	200	40.48 ± 1.14	—
5g1	200	0	—
5h	200	0	—
5i	200	69.03 ± 1.77	0.41 ± 0.04
5k1	200	43.33 ± 2.06	—

Voglibose (Merck, Germany) was employed as a positive sample.