Research Article

Comparative Transcriptomic Analyses of a Vero Cell Line in Suspension versus Adherent Culture Conditions

Table 2

Key downregulated networks and their top-associated genes (NTA) (subnetwork layouts in Figure 7).

Pathway GO IDPathway GO nameAdjusted -valueTop-ranking associated genes

GO:0009653Anatomical structure morphogenesis8.6426-8FYN, GDNF, HECW2
GO:0007167Enzyme-linked receptor protein signaling pathway0.0000018879FYN, SMAD9
GO:0030154Cell differentiation0.0000030284CAND1, FYN, GDNF, HECW2, NMT
GO:0048731System development0.0000031743FYN, GDNF, HECW2, NMT
GO:0030335Positive regulation of cell migration0.0004TRIP6
GO:0071363Cellular response to growth factor stimulus0.0002FYN, SMAD9
GO:0045860Positive regulation of protein kinase activity0.0001FYN