A Short Post-Reattachment Ultrasensitive Window of Time in Human Cancer Cells as Therapeutic Target of Prolonged Low-Dose Administration of Specific Compounds

Figure 3

Existence of a SUSWoT in H460 cells treated with nigericin. Fifty cells were plated per well and allowed to adhere overnight. Then, cells were exposed to the indicated concentrations of nigericin for 3 days followed by incubation in drug-free media for (a) 7 days, (b) 10 days, or (c) 10 days following a 3-day period of drug-free medium incubation. Afterwards, colonies were stained with crystal violet and quantified with ImageJ software (d). This figure is representative of three independent experiments.

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