Research Article

Acute Genetic Damage Induced by Ethanol and Corticosterone Seems to Modulate Hippocampal Astrocyte Signaling

Figure 2

BAX immunoreactivity after astrocyte EtOH and/or CTS injuries. (a) Confocal images of control and injured astrocytes showing BAX immunostaining. Nuclei were labeled with DAPI (blue). Calibration bar: 10 m. (b, c) Distribution of BAX signals in the cytoplasm (b) and nucleus (c) of astrocytes from the different experimental conditions. The cross lines within the boxes represent the median. Differences between 100 astrocytes per group were assessed via the Kruskal-Wallis test with Dunn test for multiple comparisons. ; ; ; ; ns. DAPI: 2-(4-amidinophenyl)-1H-indole-6-carboxamidine; CM: culture media; DMSO: dimethyl sulfoxide; EtOH: ethanol; CTS: corticosterone; EtOH+CTS: EtOH and CTS cotreatment; MGV: mean grey value.
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