The Use of Noninvasive Velacur® for Discriminating between Volunteers and Patients with Chronic Liver Disease: A Feasibility Study

Table 4

The effect of subject characteristics on IQR/median was examined for different characteristics, including type of subject (patient vs. healthy volunteer), gender, BMI, and age. Analysis was completed for both Velacur (a) and FibroScan (b) (elasticity and attenuation measures) against categorical variables. Part c shows the results of the analysis with continuous variables (BMI and age) for Velacur (left) and FibroScan (right). Significance with .

(a)

IQR/median	Statistical test	Velacur elasticity IQR/median				Velacur ACE IQR/median
		Mean IQR/median (%)		value	Sig	Mean IQR/median (%)		value	Sig
Healthy vs. patient	Rank sum	Healthy ()	Patient ()	0.13	No	Healthy ()	Patient ()	0.03	Yes
Gender	Rank sum	Male ()	Female ()	0.10	No	Male ()	Female ()	0.10	No

(b)

IQR/Median	Statistical test	FibroScan elasticity IQR/median				CAP IQR/median
		Mean IQR/median (%)			Sig	Mean IQR/median (%)			Sig
Healthy vs. patient	Rank sum	Healthy ()	Patient ()	0.13	No	Healthy ()	Patient ()	0.03	Yes
Gender	Rank sum	Male ()	Female ()	0.10	No	Male ()	Female ()	0.10	No

(c)

IQR/median	Statistical test	Velacur				FibroScan
		Elasticity IQR/median		ACE IQR/median		Elasticity IQR/median		CAP IQR/median
			Sig		Sig		Sig		Sig
BMI	Spearman correlation	0.0017	Yes	0.18	No	0.15	No	<0.001	Yes
Age	Spearman correlation	0.085	No	0.33	No	0.37	No	<0.001	Yes