Somatic Symptoms of Depression Lose Association with Mortality upon Adjustment for Frailty: Analysis from the Fitness Haemodialysis Cohort

Table 3

Incidence rate ratios of hospital admissions associated with the PHQ-9 cognitive component score. Fully adjusted model including CFS.

	HR	Lower 95% C.I.	Upper 95% C.I.	P
PHQ-9 cognitive score	0.980	0.950	1.01	0.194
Age	1.14	1.04	1.26	0.007
CFS	0.987	0.977	0.998	0.021
Gender
Male	REFERENCE
Female	0.971	0.788	1.20	0.785
Ethnicity
White	REFERENCE
South Asian	0.802	0.604	1.06	0.126
Black	0.670	0.490	0.914	0.012
Other	0.822	0.423	1.60	0.564
BMI	0.997	0.983	1.01	0.701
IMD quintile
1	REFERENCE
2	0.871	0.652	1.16	0.349
3	0.823	0.605	1.12	0.212
4	0.802	0.538	1.20	0.279
5	0.756	0.485	1.18	0.215
Unknown	1.26	0.838	1.89	0.268
Charlson index	1.09	1.02	1.16	0.007
Previous admissions	1.10	1.05	1.16	<0.001
Medication number	1.02	0.992	1.05	0.146
Smoking status
Current smoker	REFERENCE
Ex-smoker	0.840	0.598	1.18	0.318
Never smoked	0.762	0.558	1.04	0.086
Albumin	0.998	0.994	1.00	0.158
Walking aid use
No	REFERENCE
Yes	1.49	1.17	1.91	0.001
HD vintage	1.00	0.998	1.00	0.944
Transplant listed
No	REFERENCE
Yes	0.896	0.628	1.28	0.546
Constant	0.003	0.001	0.008	<0.001

Incidence rate ratios obtained by negative binomial regression. Bold text indicates significance at the P<0.05 level.