Research Article

Endovascular versus Surgical Lower Extremity Revascularization among Patients with Chronic Kidney Disease

Table 1

Baseline characteristics of patients with chronic kidney disease who received a lower extremity revascularization between January 1, 2013, and January 1, 2021, stratified by type of revascularization.

VariablesEndovascularSurgicalMaximum absolute standardized difference
N = 60,057N = 9338Before IPTWAfter IPTW

Mean age (standard deviation), years72.9 (10.1)72.3 (10.4)5.30.2
Female sex26,508 (44.1%)3747 (40.1%)8.10.4
Race and ethnicity
 Asian1225 (2.0%)158 (1.7%)3.00.4
 Black10,665 (17.8%)1448 (15.5%)6.51.0
 Hispanic8457 (14.1%)929 (10.0%)13.30.3
 White36,542 (60.9%)6318 (67.7%)15.51.1
 Missing3168 (5.3%)485 (5.2%)
Comorbid conditions
 Coronary artery disease33,210 (55.3%)5361 (57.4%)4.31.5
 Peripheral artery disease45,333 (75.5%)7072 (75.7%)
 Cerebral vascular disease13,724 (22.9%)2185 (23.4%)1.31.2
 Congestive heart failure19,996 (33.3%)3204 (34.3%)2.10.6
 Valvular disease9434 (15.7%)1804 (19.3%)9.50.3
 Hypertension, uncomplicated52,376 (87.2%)8065 (86.4%)2.51.1
 Hypertension, complicated30,607 (51.0%)4450 (47.7%)6.60.9
 Pulmonary circulation disorder2973 (5.0%)450 (4.8%)0.60.4
 Diabetes without chronic complications32,496 (54.1%)4368 (46.8%)14.70.7
 Diabetes with chronic complications35,754 (59.5%)4571 (49.0%)21.40.4
 Chronic pulmonary disease17,974 (29.9%)3314 (35.5%)11.91.0
 Liver disease2689 (4.5%)453 (4.9%)1.80.2
 Chronic peptic ulcer disease1082 (1.8%)218 (2.3%)3.70.5
 Neurological8540 (14.2%)1306 (14.0%)0.70.4
 Hypothyroidism10,136 (16.9%)1425 (15.3%)4.40.6
 HIV and AIDS224 (0.4%)39 (0.4%)0.70.4
 Lymphoma679 (1.1%)121 (1.3%)1.50.4
 Metastatic cancer1081 (1.8%)194 (2.1%)2.00.2
 Solid tumor without metastasis5763 (9.6%)1043 (11.2%)5.20.1
 Rheumatoid arthritis/collagen vascular diseases3552 (5.9%)512 (5.5%)1.90.1
 Obesity12,713 (21.2%)1805 (19.3%)4.60.3
 Weight loss5106 (8.5%)922 (9.9%)4.80.3
 Fluid and electrolyte disorders20,759 (34.6%)3417 (36.6%)4.20
 Coagulation deficiency6313 (10.5%)1130 (12.1%)5.01.2
 Blood loss anemia2259 (3.8%)431 (4.6%)4.30.1
 Deficiency anemia23,182 (38.6%)3340 (35.8%)5.90.5
 Alcohol abuse1575 (2.6%)355 (3.8%)6.70.3
 Drug abuse1331 (2.2%)251 (2.7%)3.10.3
 Psychoses2573 (4.3%)446 (4.8%)2.40.2
 Depression9424 (15.7%)1519 (16.3%)1.60.3
 Paralysis3136 (5.2%)458 (4.9%)1.40.1

All values are N (%) except where indicated. Standardized differences are estimated from the maximum absolute difference between the endovascular and surgical covariates for the 5 imputed datasets. IPTW = inverse probability of treatment weighting.