Immunophenotypic Characterization of Citrate-Containing A Concentrates in Maintenance Hemodialysis: A Pre-Post Study
Table 1
Baseline characteristics of the study population.
Parameters
Total N = 61
Unit 1 N = 35
Unit 2 N = 26
value
Age (years; mean ± SD)
69.9 ± 15.6
69.6 ± 16.6
70.2 ± 14.6
0.90
Gender, male (n%)
30 (49.2)
19 (54.3)
11 (42.3)
0.36
BMI (kg/m2, mean ± SD)
25.8 ± 4.8
25.9 ± 5.0
25.7 ± 4.6
0.86
Dialysis vintage (months; median, IQR)
34 (15.59)
38 (17.58)
29 (14.61)
0.67
Anuric (n%)
14 (23.0)
5 (14.3)
9 (34.6)
0.06
Overweight (n%)
30 (49.2)
16 (45.7)
14 (53.8)
0.53
CCI
4 (2.8)
6 (3.8)
2.5 (1.7)
0.16
Arteriosclerosis (n%)
22 (36.1)
15 (42.9)
7 (26.9)
0.20
Coronary heart disease (n%)
20 (32.8)
13 (37.1)
7 (26.9)
0.40
Diabetes mellitus (n%)
20 (32.8)
13 (37.1)
7 (26.9)
0.40
History of myocardial infarction (n%)
11 (18.0)
7 (20)
4 (15.4)
0.65
Central vascular disease (n%)
12 (19.7)
7 (20)
5 (19.2)
0.94
Heart failure (n%)
5 (8.2)
3 (8.6)
2 (7.7)
0.90
Pulmonary hypertension (n%)
7 (11.5)
5 (14.3)
2 (7.7)
0.43
Atrial fibrillation (n%)
16 (26.2)
10 (28.6)
6 (23.1)
0.63
COPD (n%)
6 (9.8)
6 (17.1)
0 (0)
0.03
Peripheral arterial disease (n%)
11 (18)
7 (20.0)
4 (15.4)
0.65
Medication
Immunosuppressive medication (n%)
22 (36.1)
11 (31.4)
11 (42.3)
0.39
Glucocorticoid (GC)
7 (11.5)
1 (2.9)
6 (23.1)
NSAIDs
13 (21.3)
9 (25.7)
4 (15.4)
Tacrolimus
1 (1.6)
1 (2.9)
0
Mycophenolate mofetil
1 (1.6)
0
1 (3.8)
GC + MMF + NSAID
1 (1.6)
0
1 (3.8)
Statin (n%)
29 (47.5)
17 (48.6)
12 (46.2)
0.85
Blood pressure medication (n%)
58 (95.1)
33 (94.3)
25 (96.2)
0.74
Patients required hospitalization due to infectious events within 24 monthsb
15 (24.6)
12 (34.3)
3 (11.5)
0.05
Body mass index (BMI); Carlson comorbidity index (CCI); chronic obstructive pulmonary disease (COPD); nonsteroidal anti-inflammatory drugs (NSAIDs). Values are given as either mean ± standard deviation or number (percentage) or median (IQR). The independent-samples t-test and the Wilcoxon–Mann–Whitney U test were used for comparison of dialysis units at baseline. < 0.05 was considered significant. aOne patient was prescribed combined immunosuppressive treatment. b1 missing value.
