International Journal of Rheumatology / 2022 / Article / Tab 1 / Review Article
Effect of Polymorphisms in the FCN1, FCN2, and FCN3 Genes on the Susceptibility to Develop Rheumatoid Arthritis: A Systematic Review Table 1 Data from studies included in the systematic review.
Author Year Gene Genetic variants Geographic region Study type Source of controls NOS Number of cases Number of controls Pieczarka et al. [11 ] 2015 FCN1 FCN2 rs2989727 rs1071583 rs17514136 rs3124954 rs7851696 Brazil Cases and controls Community 9 184 264 Addobbati et al. [12 ] 2020 FCN1 FCN3 rs2989727 rs10120023 rs17039495 rs10117466 rs10858293 rs532781899 rs28362807 rs4494157 Brazil Cases and controls Community 9 148 160 Vander Cruyssen et al. [13 ] 2007 FCN1 FCN2 FCN3 rs2989727 rs1071583 rs7865453 ss32469537 ss32469544 rs7851696 rs3813800 Belgium Cases and controls Community 9 338 595
The variants are described according to their RS code (RefSNP) assigned in dbSNP (genetic variant database of the US National Institutes of Health). Available at
https://www.ncbi.nlm.nih.gov/snp/ .
Score on the Newcastle-Ottawa scale (NOS).