Research Article
Prognostic Impact of Tumor Budding on Moroccan Colon Cancer Patients
Table 5
Association between tumor budding and clinicopathological features.
| Variables | Low-grade tumor budding | High-grade tumor budding | value |
| Age | | | 0.03 | <57 | 36 (60.0%) | 17 (42.5%) | ≥57 | 24 (40.0%) | 23 (57.5%) | Genre | | | 0.2 | Female | 28 (46.7%) | 15 (37.5%) | Male | 32 (53.3%) | 25 (62.5%) | Tumor site | | | 0.4 | Right colon | 22 (36.7%) | 16 (40.0%) | Left colon | 38 (63.3%) | 24 (60.0%) | Histologic subtype | | | 0.2 | Adenocarcinoma | 54 (90.0%) | 32 (80.0%) | Mucinous | 3 (5.0%) | 6 (15.0%) | Others | 3 (5.0%) | 2 (5.0%) | Histologic grade | | | 0.5 | Well | 28 (46.7%) | 18 (45.0%) | Moderate | 26 (43.3%) | 20 (50.0%) | Poor | 6 (10.0%) | 2 (5.0%) | Venous invasion | | | 0.05 | Presence | 9 (15.3%) | 11 (28.2%) | Absence | 50 (84.7%) | 28 (71.8%) | Perineural invasion | | | 0.02 | Presence | 5 (8.5%) | 10 (25.6%) | Absence | 54 (91.5%) | 29 (74.4%) | Number of removed lymph nodes | | | | Mean (SD) | 21.7 (±8.5) | 19.2 (±6.9) | 0.2 | ˂12 | 5 (8.6%) | 7 (17.9%) | 0.1 | ˃12 | 53 (91.4%) | 32 (82.1%) | | Positive lymph node | | | | Mean (SD) | 1.2 (±0.0) | 1.4 (±2.9) | 0.8 | Presence | 19 (32.2%) | 13 (33.3%) | 0.5 | Absence | 40 (67.8%) | 26 (66.7%) | | RGL | | | | Mean (SD) | 0.06 (±0.03) | 0.063 (±0.2) | 0.9 | Synchronous metastasis (M) | | | ˂0.001 | M0 | 57 (95.0%) | 26 (66.7%) | M1 | 3 (5.0%) | 13 (33.3%) | Disease stages | | | 0.001 | I | 2 (3.3%) | 2 ((5.0%) | II | 37 (61.7%) | 15 (37.5%) | III | 18 (30.0%) | 9 (22.5%) | IV | 3 (5.0%) | 14 (35.0%) | Follow-up time (months) | 27.0 (±19.3) | 24.8 (±13.3) | 0.7 | Recurrence | | | | (+) | 14 (23.3%) | 15 (38.5%) | 0.04 | (−) | 46 (76.7%) | 24 (61.5%) | | Recurrence patterns | | | | Liver | 2 (14.3%) | 3 (20%) | 0.07 | Lung | 3 (21.4%) | 3 (20%) | | Peritoneum | 2 (14.3%) | 5 (33.3%) | | Local recurrence | 6 (42.9%) | 3 (20%) | | Others | 1 (7.1%) | 1 (6.7%) | | Mortality | | | 0.02 | Death cases | 7 (11.7%) | 11 (28.2%) | Censored cases | 53 (88.3%) | 28 (71.8%) |
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