Research Article
Development and Validation of Analytical Procedure for Elemental Impurities in Rosuvastatin Calcium Tablets by ICP-MS and Microwave Digestion
Table 5
Selection of elements’ isotopes.
| Element | Isotopes abundance ratio | Potential interference | Selected |
| Cd | 114Cd (28.73%) | 114Cd: 40Ar + 74Ge, 12C + 102Ru, 16O + 98Mo | 111Cd | 112Cd (24.13%) | 112Cd: 40Ar + 72Ge, 14N + 98Mo, 16O + 96Mo | 111Cd (12.80%) |
| Pb | 208Pb (52.40%) | None | 208Pb | 206Pb (24.10%) | 207Pb (22.10%) |
| As | 75As (100%) | None | 75As |
| Hg | 202Hg (29.80%) | None | 202Hg | 200Hg (23.13%) | 199Hg (16.84%) |
| Co | 59Co (100%) | None | 59Co |
| V | 51V (99.75%), 50V (0.25%) | None | 51V |
| Ni | 58Ni (68.27%) | 58Ni: 58Fe, 40Ar + 18O | 60Ni | 60Ni (26.10%) | 61Ni (1.13%) |
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