Research Article
Development and Validation of Analytical Procedure for Elemental Impurities in Rosuvastatin Calcium Tablets by ICP-MS and Microwave Digestion
Table 6
Results of linearity, range, and LOQ.
| Element | Range | Equations | | LOQ (µg L−1) |
| 111Cd | 0∼2.5 µg·L−1 | f (x) = 9292.8026x + 11.3308 | 0.9996 | 0.25 | 208Pb | 0∼2.5 µg·L−1 | f (x) = 177518.3179x + 7591.9806 | 1.0000 | 0.25 | 75As | 0∼7.5 µg·L−1 | f (x) = 2139.7435x + 6.9935 | 0.9999 | 0.75 | 202Hg | 0∼15 µg·L−1 | f (x) = 34197.1263x + 688.0450 | 0.9999 | 1.5 | 59Co | 0∼25 µg·L−1 | f (x) = 45810.3360x + 241.2838 | 0.9999 | 2.5 | 51V | 0∼50 µg·L−1 | f (x) = 14661.8418x + 64.3682 | 0.9999 | 5.0 | 60Ni | 0∼100 µg·L−1 | f (x) = 13025.5736x + 3519.1796 | 0.9998 | 10 |
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