Research Article
Development and Validation of Analytical Procedure for Elemental Impurities in Rosuvastatin Calcium Tablets by ICP-MS and Microwave Digestion
Table 9
Precision of 7 elements in rosuvastatin calcium tablets.
| Matrix | Recovery (%) | Cd | Pb | As | Hg | Co | V | Ni |
| Interday | 99.8 | 100.9 | 95.1 | 95.6 | 97.1 | 99.1 | 97.1 | 99.0 | 101.8 | 94.8 | 93.6 | 96.6 | 97.9 | 96.5 | 101.5 | 103.6 | 96.6 | 93.0 | 96.4 | 97.2 | 96.7 | 97.3 | 101.6 | 94.6 | 92.2 | 95.4 | 96.4 | 95.5 | 96.9 | 102.1 | 95.3 | 91.3 | 95.3 | 98.3 | 96.0 | 100.4 | 101.2 | 96.2 | 90.2 | 96.5 | 96.3 | 95.8 |
| Intraday | 99.7 | 99.8 | 93.3 | 95.6 | 96.2 | 97.2 | 96.8 | 98.9 | 100.1 | 95.6 | 93.3 | 94.9 | 97.6 | 95.9 | 100.2 | 105.3 | 94.6 | 92.8 | 95.7 | 98.0 | 94.7 | 101.1 | 102.9 | 93.3 | 91.9 | 93.9 | 96.9 | 96.3 | 99.7 | 104.5 | 95.8 | 94.6 | 96.1 | 94.9 | 96.8 | 98.6 | 99.9 | 96.0 | 94.3 | 95.6 | 95.6 | 95.9 |
| RSD (%) | 1.4 | 1.8 | 1.1 | 1.8 | 0.9 | 1.2 | 0.7 |
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