Journal of Diabetes Research / 2024 / Article / Tab 1 / Research Article
Impaired Sensitivity to Thyroid Hormones Is Associated With the Change of Abdominal Fat in Euthyroid Type 2 Diabetes Patients: A Retrospective Cohort Study Table 1 Characteristics of patients at baseline.
Characteristics ( ) At baseline Age (years) 50.43 (11.86) Duration (years) 4.5 (0.4, 10.9) Male ( , %) 554 (60.2) Current smoker ( , %) 313 (34.1) Current drinker ( , %) 374 (40.7) Hypertension ( , %) 366 (40.5) BMI (kg/m2 ) 26.98 (4.03) VFA (cm2 ) 108.21 (43.50) SFA (cm2 ) 209.63 (71.18) Laboratory test HbA1c 8.18 (2.69) Cr (μ mol/L) 67.26 (15.70) LDL-c (mmol/L) 3.03 (0.90) fT4 (pmol/L) 16.73 (1.97) fT3 (pmol/L) 4.61 (0.61) TSH (mIU/L) 1.83 (0.88) Antihyperglycemic agent Insulin/sulfonylureas ( , %) 693 (75.2) GLP1-RA/SGLT2i ( , %) 34 (3.7) At last visit of follow-up BMI (kg/m2 ) 26.92 (6.76) VFA (cm2 ) 106.94 (41.59) SFA (cm2 ) 200.15 (69.34) Change of BMI (kg/m2 ) −0.07 (5.79) Change of VFA (cm2 ) −1.27 (32.26) Change of SFA (cm2 ) −9.48 (43.85) Change rate of BMI (kg/m2 per year) 0.14 (6.37) Change rate of VFA (cm2 per year) −0.40 (18.04) Change rate of SFA (cm2 per year) −4.52 (25.55) Follow-up period (years) 2.2 (1.8, 3.0)
Abbreviations: BMI, body mass index; fT3, free triiodothyronine; fT4, free thyroxine; GLP1-RA, glucagon-like peptide-1 receptor agonists; LDL-c, low-density lipoprotein cholesterol; SFA, subcutaneous fat area; SGLT2i, sodium-glucose cotransporter 2 inhibitors; TSH, thyroid stimulating hormone; VFA, visceral fat area.